The Entourage Effect Of CBD Oil And Why Canada Loves It

The popularity of CBD oil in Canada can make you overlook some of the tiniest elements within the plant. In fact, not many that the simple aromatic leaves contain more than 80 cannabinoids and terpenes.

Also, if you examine this plant closely, you will discover that there are a lot of mechanisms at work. Marijuana has many other molecular compounds within it, not just the common Tetrahydrocannabinol (THC) and Cannabidiol (CBD) that many people are familiar with. There are terpenes, vitamins, minerals, fatty acids, flavonoids and other cannabinoids that are also beneficial.

CBD oil is absolutely amazing as a product.

The synergy produced when all these compounds work together, and within the human body, brings about the entourage effect that is felt from full-spectrum CBD.

In this article, we seek to explore the entourage effect and understand its function in the human body when it is taking CBD.

cbd box and dropper bottle

What is the entourage effect?

The entourage effect was first discovered and mentioned by two Israeli scientists in 1998, Shimon Ben-Shabat and Raphael Mechoulam.

Cannabinoids and terpenes found in the cannabis plant can either work together or singularly within the human body. When they work jointly, they produce a stronger effect, which is what we refer to as the Entourage Effect.

Combining these multiple compounds in their natural form, often results in a multiplying effect. The different components, upon interacting, tend to intensify each other’s properties, bringing about therapeutic effects.

Understanding the various components in cannabidiol is necessary for realizing their roles in your body.

Understanding The Makeup Of Canadian CBD Oils

Researchers in Toronto have long been trying to isolate CBD’s sister compounds.

Ever since an Ottawa scientist brought terpenes and other cannabinoids to fellow Canucks, the country has been going absolutely nuts trying to figure out just exactly HOW CBD helps the body reduce inflammation(and Justin Trudeau should learn about CBD oil too!).

The cannabis plant is available in different strains. The entourage effect can help us comprehend why certain strains of marijuana can affect people differently. The chemical properties found in various strains can also cause different reactions for one individual.

CBD oil is enjoyed by people from all walks of life.

This is evident as a marijuana user can at times feels calm, and other times paranoid, depending on the particular strain of cannabis consumed.

Canada boasts a huge array of various cannabis strains(since the herb is now officially legal here) and this abundance of raw product ends up aiding the CBD product selection as well.

All these new Canadian-made cannabis oil products are great because they can be ordered anywhere, from Toronto to Ottawa, and they ship right to your door quickly and also offer great discounts.

We absolutely love the fact that this country is now accepting CAD for all CBD products and Justin Trudeau also loves to order these hemp products online right to his house in Vancouver.

Each strain of the marijuana plant contains hundreds of cannabinoids and terpenes which act together to amplify the plant’s effects.

When you change the composition of a specific strain, you change the effects as well.

There are many different cannabinoids and terpenes to learn about aside from just Cannabidiol.


Terpenes are the components that are responsible for scent production in the marijuana plant. The plant’s compelling fragrance and psychoactive flavor are determined by the various terpenes found in a strain.

There are over 200 different types of terpenoids including diterpenes and monoterpene. They consist of a 5-carbon molecule known as isoprene. Terpenoid profile, however, can vary significantly from strain to strain depending on the Tetrahydrocannabinol (THC) and or Cannabidiol (CBD) content.

As it turns out, terpenes are beneficial to human beings and plants as well. Marijuana’s pungent terpenoid oils have helped it ward off fungus, insects and animal grazers giving it survival advantages. Moreover, in human beings, terpenes bind to the cannabinoid receptors in the endocannabinoid system.When they combine, the terpenes and cannabinoids produce synergy. This helps in killing pathogens, increasing blood flow and treatingpain, inflammation, depression, anxiety, cancer among other illnesses.

Another important role played by terpenes is that they combine with CBD to alter the psychoactive effects of THC.

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hemp seeds and cannabis oil

The relationship between THC (Tetrahydrocannabinol) and CBD (Cannabidiol)

CBD interacts with various components of the endogenous cannabinoid system to boost the central nervous system in the body. Since CBD is not intoxicating at the molecular level, its effects are the reverse of THC, which is a psychoactive element.

So, how does CBD offset the psychoactive effects of THC? The body has two types of receptors. These are the CB1 (receptors in the brain and CNS) and CB2 (receptors in the immune system).  When CBD binds to CB1 and CB2 cannabinoid elements, it acts as an inverse agonist. This means that it attaches to the active receptors, acting as a stabilizer to reduce their harmful activities. The binding process explains why we experience the effects of using marijuana like the relaxation feelings.

The relationship between CBD and THC can seem a bit complex. Overall, CBD tends to minimize the harsh effects of THC such as paranoia and impaired thinking.

A study was conducted in 1976 to show how CBD reduces the psychoactive effects of THC. The researchers administered THC and a high dose of CBD.11 out of the 15 test subjects said that they felt a stronger psychoactive effect when taking THC alone, than when the dose of CBD was higher than that of THC. This is because when THC binds with receptors in the brain, it amplifies that high feeling.

Combining THC and CBD, therefore, yields better results in Canadian patients than when THC is used in isolation. The entourage effect is evident here as the different cannabinoid molecules work together to achieve more efficient results.

Full Spectrum vs. Isolate CBD: Which Yields a Better Entourage Effect?

Whole plant medicine is a concept that herbalists have managed to perfect over the years. It has been proven to yield better results than pharmaceutical drugs since, traditional herbs focus on whole plant medicine.

So, to get the most from your marijuana experience, you can take full spectrum CBD oil, smoke it or vape it. This is contrary to taking the isolate form of CBD.

Final Thoughts

CBD oil is available in all different forms all throughout Canada. It also contains hundreds of chemical compounds such as flavonoids, terpenes and cannabinoids. These elements all work together to produce more significant effects than they would if they were used individually.

Studies have indicated how different terpenes have particular impacts in the bloodstream and brain. Taking CBD oil can help you immensely with various conditions. This sheds light on how certain cannabinoids operate more efficiently when they do not work in isolation.

However, researchers agree that the entourage effect is not a concept that has been fully understood in CBD oils. Medical practitioners are advised to use an extensive range of medication with a low dosage to treat a variety of ailments. This is in reverse with what doctors are used to in western medicine procedures, whereby they prescribe a specific compound to cure a single disease.

The whole plant medication concept of CBD oil, despite being a new concept, may be subject to debate between medical practitioners and researchers. That said, the science field is open to exploration with over 500 different species of cannabis in the world. Further research can lead to the creation of new and effective remedies for CBD users.

2 New CBD Oil Brands Reviewed: Bluebird Botanicals vs. CBDistillery

CBD oil is fast becoming a medical wonder with the countless positive reviews about it and the growing list of US states that support the legalization of medical cannabis. Even the experts are relentless in their pursuit of getting a better understanding of cannabis with scientific studies and research to ensure the public’s safety and well-being. And it seems that we are up for a treat as studies prove what we know of CBD to be true as it really comes in handy in treating and managing a diverse list of ailments.

There are many great brands, including Bluebird Botanicals, CBDistillery, Green Roads, and Pure Kana.

We see it as a blessing in disguise seeing how it has reclaimed its nasty reputation of being a regulated substance that causes unnatural highs and highly addicting too but it does not mean that it is perfect. And there is a lot of truth to rumors about marijuana back then since it was only used recreationally but the tide has turned now and CBD is even prescribed by doctors to their patients. Yet, CBD oil has its flaws but it is up to you to weigh whether it is alright to overlook these imperfections and take it especially if you have a few options left. A lot of people are wondering, what is CBD/hemp oil?

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cbd gummies

However, ignorance should never be an excuse, so it is a must for you to be aware of potential risks and side effects before taking anything even for something as popular and well-received like CBD oil so you won’t have anything to blame for later when you experience it for yourself. Since it is a natural remedy and has long been used in the East in the treatment of human maladies, its side effects aren’t really life-threatening but enough to cause a minor discomfort in your life. These side effects are also more common if you don’t follow your doctor’s order and take the wrong dosage or not the best route to address your condition.

bluebird botanicals cbd oil

Bluebird Botanicals CBD Oil: A Review

It is actually quite an irony to discuss CBD oil side effects considering that CBD oil is preferred by many since unlike other cannabis, it is not addicting or has psychoactive properties.

In reality, it is the second most known active component of cannabis next to THC. CBD does not have a lot of side effects but it is worth knowing what they are rather than blindly take something and be surprised if you feel some discomfort after. These side effects are inevitable especially that there are powerful chemicals in it that interacts with certain body processes. It is the same thing with every other medicine you take, whether prescription or over-the-counter. Bluebird’s brand has been around for quite some time, and that is why people really trust it.

You can experience mild side effects while others may experience more serious ones and several symptoms at a time, it’s all a case-to-case basis. Interaction with other drugs may also play a role as to the severity of the side effects. But there’s no reason to be scared as most side effects are generally mild in nature and can easily be overlooked or ignored by most people. We recommend Bluebird Botanicals’ CBD oil, but you really do need to make the right selection.

Potential Side Effects Of Bluebird Botanicals’ CBD Products

• Dry Mouth – otherwise known as “cotton mouth”, having a dry mouth is one of the most common side effects felt by individuals who take cannabis orally but it is more aptly called as “xerostamia” in scientific terms. CBD interacts with cannabinoid receptors presents in the submandibular gland that is directly related to saliva production, leading to a reduced production of the saliva of the user. Increase your fluid intake to combat dry mouth or chew a sugar-free gum to stimulate saliva production.

• Lower Blood Pressure – this is often not considered as a side effect among people with hypertension as it helps reduce blood pressure levels and prevent it from shooting up. Also, you may only experience low blood pressure when taking cannabis if you have been taking higher than normal dosages of cannabis than prescribed. If you are sticking to your doctor’s orders, you won’t have to deal with any fluctuations in your blood pressure at all.

• Drowsiness – feeling drowsy is a symptom experienced by some. You may not get that unnatural high from THC-rich cannabis but it is normal to experience drowsiness at times when taking medical cannabis. It should not be much of an issue for you, though, if you apply it topically. However, you should exercise a few precautions and avoid going on long drives or operating a machinery in case you may feel drowsy all of a sudden.

cbdistillery cbd oil

CBDistillery CBD Oil Reviewed

You can get gummies, tinctures, and pills of cannabidiol from CBDistillery.

While CBD oil is often used topically, it can also be taken by mouth so it is possible for you to experience these side effects yourself when taking medical cannabis. Other side effects of CBDistillery’s cannabidiol products you should be wary of are the following:

• Lightheadedness
• Dysphoria
• Tiredness
• Mild stomach upset
• Increased tremors in patients with Parkinson’s Disease
• Reduced hepatic drug metabolism

Like any other substance taken by people to help them manage certain diseases or to boost their health, CBD oil has its pros and cons especially when you consume a higher dosage than indicated for your condition. Moreover, how pure the CBD oil you are taking also has an impact on the severity of side effects experienced by users. Remember that a carrier oil is often used in making CBD oil, so it is not entirely pure.

Compared to Bluebird Botanicals, CBDistillery just doesn’t pack quite the same punch.


Oh, and don’t worry! The legality of medical marijuana products is drastically increasing.

Now that you are aware what these side effects are, don’t let them stop you from taking CBD oil if it has been proven to be of big help to your health and well-being. Other drugs out there are more toxic than CBD oil but people still take it. It is all about weighing the dangers and what your options are. And most feedbacks say that CBD oil side effects are generally well tolerated. You seldom hear about them too because they aren’t that big of an issue in the use of CBD oil. Also, there are plenty of studies being conducted on the safety and efficacy of CBD oil, so we can be sure that people are curious and want to know more about it. With that being said, the whole world will know about any new developments and findings regarding CBD oil, if it truly is a miracle cure to make chronic diseases that plague mankind.